Full Transparency|Updated June 16, 2026

Cholibrium Ingredients: The Complete 10-Mushroom Breakdown

Every ingredient in Cholibrium is backed by published research. Here's a complete breakdown of all 10 mushroom extracts, their traditional uses, modern research, and how they work together to support heart health.

Cholibrium Contains 10 Mushroom Extracts:

1.Reishi(Ganoderma lucidum)
2.Lion's Mane(Hericium erinaceus)
3.Cordyceps(Cordyceps sinensis)
4.Shiitake(Lentinus edodes)
5.Maitake(Grifola frondosa)
6.Turkey Tail(Trametes versicolor)
7.Chaga(Inonotus obliquus)
8.Royal Agaricus(Agaricus blazei)
9.White Button Mushroom(Agaricus bisporus)
10.Black Fungus(Auricularia auricula)

The 10 Mushroom Ingredients in Cholibrium

Reishi

Immune modulation & cholesterol support

Scientific name: Ganoderma lucidum

Also known as: Lingzhi

What it does:

One of the most studied medicinal mushrooms on the planet. Reishi contains triterpenes and polysaccharides that researchers have linked to immune modulation and cardiovascular support.

What the research says:

A study published in the World Journal of Gastroenterology found that reishi may increase HDL (good) cholesterol and decrease triglycerides. Other research points to its adaptogenic properties, helping the body manage stress responses that can affect heart health.

Traditional use:

Used for over 2,000 years in Traditional Chinese Medicine as the 'Mushroom of Immortality.' Prized for promoting longevity, immune health, and calm energy.

How it works:

Reishi's beta-glucans and triterpenes work together to modulate immune response and support healthy cholesterol metabolism. The triterpenes specifically may help reduce inflammation in blood vessels.

Cholibrium dose: 266 mg per serving

Lion's Mane

Cognitive function & triglyceride management

Scientific name: Hericium erinaceus

Also known as: Hedgehog mushroom

What it does:

Known primarily for cognitive benefits, Lion's Mane also plays a role in cardiovascular health through fat metabolism support.

What the research says:

Research shows Lion's Mane can help lower triglyceride levels. High triglycerides are a risk factor for blood clots and heart attacks. The mushroom contains hericenones and erinacines, compounds that support nerve growth factor.

Traditional use:

Used in East Asian medicine for digestive health and as a brain tonic. Buddhist monks used it to enhance concentration during meditation.

How it works:

Lion's Mane stimulates Nerve Growth Factor (NGF) production, which benefits both brain and cardiovascular health. Its polysaccharides also support healthy fat metabolism.

Cholibrium dose: 266 mg per serving

Cordyceps

Energy, endurance & circulation

Scientific name: Cordyceps sinensis

Also known as: Caterpillar fungus

What it does:

An adaptogenic fungus used in traditional Chinese medicine for energy and endurance. Cordyceps supports how your body uses oxygen during physical activity.

What the research says:

Studies suggest Cordyceps may improve blood circulation, reduce oxidative damage to blood vessels, and support oxygen utilization in tissues. Some research links it to improved endurance and reduced fatigue.

Traditional use:

Prized in Tibetan and Chinese medicine for centuries. Used to support lung function, energy, and athletic performance. Historically harvested from caterpillars in the Himalayas.

How it works:

Cordyceps increases ATP production in cells, improving how your body uses oxygen. This supports cardiovascular efficiency and energy levels throughout the day.

Cholibrium dose: 266 mg per serving

Shiitake

Cholesterol management via eritadenine

Scientific name: Lentinus edodes

Also known as: Chinese black mushroom

What it does:

A culinary mushroom with genuine medicinal properties. Shiitake contains eritadenine, a compound specifically studied for cholesterol management.

What the research says:

Eritadenine has been shown to help maintain healthy cholesterol levels by reducing cholesterol absorption in the intestines. Shiitake also contains beta-glucans that support immune function and digestive health.

Traditional use:

One of the most widely cultivated mushrooms in the world. Used in Asian cuisine and medicine for over 1,000 years. Prized for both flavor and health properties.

How it works:

Eritadenine in Shiitake inhibits an enzyme involved in cholesterol metabolism, helping maintain healthy LDL and HDL levels. Beta-glucans provide additional immune support.

Cholibrium dose: 266 mg per serving

Maitake

Cholesterol & blood sugar regulation

Scientific name: Grifola frondosa

Also known as: Dancing mushroom

What it does:

A mushroom with a strong research base for both cholesterol management and blood sugar regulation.

What the research says:

Maitake reduces triglycerides, improves fat metabolism, and enhances HDL production. It also has mild insulin-sensitizing properties. This matters because poor blood sugar regulation and high cholesterol often go together.

Traditional use:

Named 'dancing mushroom' because people allegedly danced with joy upon finding it in the wild. Used in Japanese and Chinese medicine for immune and metabolic support.

How it works:

Maitake's D-fraction beta-glucans support both immune function and metabolic health. The compound helps regulate how the body processes fats and sugars.

Cholibrium dose: Included in proprietary blend

Turkey Tail

Antioxidant protection & immune support

Scientific name: Trametes versicolor

Also known as: Coriolus versicolor

What it does:

One of the most antioxidant-rich mushrooms available. Turkey Tail contains over 35 different antioxidant compounds.

What the research says:

Research shows Turkey Tail may help reduce oxidative stress, a contributing factor in cardiovascular disease. It also supports immune function and gut health through its polysaccharopeptide content.

Traditional use:

Used in Traditional Chinese Medicine for centuries as a qi tonic. One of the most researched medicinal mushrooms, particularly for immune support.

How it works:

Turkey Tail's PSK and PSP polysaccharides provide powerful antioxidant protection. These compounds help neutralize free radicals that can damage blood vessels and contribute to cardiovascular disease.

Cholibrium dose: Included in proprietary blend

Chaga

Antioxidant support & LDL reduction

Scientific name: Inonotus obliquus

Also known as: Black diamond mushroom

What it does:

A fungus that grows on birch trees, used for centuries in Siberian and Asian traditional medicine.

What the research says:

Studies suggest Chaga extract may reduce LDL (bad) cholesterol, increase antioxidant levels in the body, and lower the risk of heart disease. It contains superoxide dismutase (SOD), a powerful antioxidant enzyme.

Traditional use:

Used in Siberian and Russian folk medicine for centuries. Known as the 'King of Mushrooms' for its potent antioxidant properties. Traditionally brewed as tea.

How it works:

Chaga contains one of the highest concentrations of antioxidants found in nature, including superoxide dismutase (SOD). This helps reduce oxidative stress and supports healthy cholesterol levels.

Cholibrium dose: Included in proprietary blend

Royal Agaricus

Immune support & blood pressure

Scientific name: Agaricus blazei

Also known as: Brazilian mushroom

What it does:

Originating from Brazil, this mushroom has been studied for its beta-glucan content and immune-supporting properties.

What the research says:

The beta-glucans in Royal Agaricus may support cardiovascular health and healthy blood pressure levels. It also contains antioxidants that help protect against oxidative damage.

Traditional use:

Discovered in the rainforest region of Brazil, where locals used it for general health and vitality. Gained international attention for its high beta-glucan content.

How it works:

Royal Agaricus contains high levels of beta-1,6-D-glucan, which supports immune function and may help maintain healthy blood pressure through improved vascular health.

Cholibrium dose: Included in proprietary blend

White Button Mushroom

Cholesterol management via beta-glucans

Scientific name: Agaricus bisporus

Also known as: Common button mushroom

What it does:

The most widely consumed mushroom in the world. Don't let the familiarity fool you — it has genuine heart-health benefits.

What the research says:

White Button mushrooms contain high levels of beta-glucan, a compound studied for its ability to support healthy cholesterol levels. They also contain conjugated linoleic acid (CLA), which has been studied for metabolic benefits.

Traditional use:

The world's most popular mushroom, cultivated for thousands of years. While primarily known as a food, it has a long history of medicinal use in various cultures.

How it works:

White Button's beta-glucans bind to bile acids in the digestive tract, helping reduce cholesterol absorption. CLA supports healthy metabolism and body composition.

Cholibrium dose: Included in proprietary blend

Black Fungus

Blood flow & circulation support

Scientific name: Auricularia auricula

Also known as: Tree ear mushroom

What it does:

A staple in Asian cuisine and traditional medicine for centuries. Also known as wood ear mushroom.

What the research says:

Polysaccharides found in Black Fungus may help manage blood cholesterol and triglycerides, support healthy blood flow, and contribute to cardiovascular wellness. Some research suggests it has mild anticoagulant properties.

Traditional use:

A staple in Chinese cuisine and medicine for over 1,400 years. Used to support blood circulation and cardiovascular health. Often added to soups and stir-fries.

How it works:

Black Fungus polysaccharides have anticoagulant properties that support healthy blood flow. The mushroom also contains compounds that may help reduce blood viscosity and support circulation.

Cholibrium dose: Included in proprietary blend

How the Ingredients Work Together

Cholesterol Balance

Shiitake's eritadenine reduces cholesterol absorption. Maitake improves fat metabolism and HDL production. White Button's beta-glucans support healthy cholesterol levels. These three mushrooms work on different parts of the cholesterol equation simultaneously.

Antioxidant Protection

Turkey Tail brings 35+ antioxidant compounds. Chaga provides superoxide dismutase. Royal Agaricus adds its own antioxidant profile. Oxidative stress damages blood vessels over time, and these compounds help neutralize the free radicals causing that damage.

Energy and Circulation

Cordyceps improves how your body uses oxygen and supports blood circulation. Reishi helps manage stress responses. Users frequently report higher energy levels within the first few weeks, which tracks with how these mushrooms affect cellular energy production.

Immune Modulation

Beta-glucans from multiple mushrooms in the formula support immune function. This matters for heart health because chronic low-grade inflammation contributes to cardiovascular disease. The immune system and cardiovascular system are more connected than most people realize.

Cholibrium Supplement Facts

Supplement Facts

Serving Size: 2 Capsules

Servings Per Container: 30

Cholibrium Proprietary Blend1,066 mg

Reishi Mushroom Extract (Ganoderma lucidum) (fruit body)

Lion's Mane Extract (Hericium erinaceus) (fruit body)

Cordyceps Extract (Cordyceps sinensis) (fruit body)

Shiitake Mushroom Extract (Lentinus edodes) (fruit body)

Maitake Extract (Grifola frondosa) (fruit body)

Turkey Tail Extract (Trametes versicolor) (fruit body)

Chaga Extract (Inonotus obliquus) (sclerotia)

Royal Agaricus Extract (Agaricus blazei) (fruit body)

White Button Mushroom Extract (Agaricus bisporus) (fruit body)

Black Fungus Extract (Auricularia auricula) (fruit body)

Other Ingredients: Hypromellose (vegetable capsule), rice flour, magnesium stearate, silicon dioxide.

Does Not Contain: Gluten, dairy, soy, GMOs, stimulants, artificial colors, artificial flavors, preservatives.

Frequently Asked Questions About Cholibrium Ingredients

What are the ingredients in Cholibrium?

Cholibrium contains 10 mushroom extracts: Reishi (Ganoderma lucidum), Lion's Mane (Hericium erinaceus), Cordyceps (Cordyceps sinensis), Shiitake (Lentinus edodes), Maitake (Grifola frondosa), Turkey Tail (Trametes versicolor), Chaga (Inonotus obliquus), Royal Agaricus (Agaricus blazei), White Button (Agaricus bisporus), and Black Fungus (Auricularia auricula).

How much Reishi is in Cholibrium?

Cholibrium contains 266 mg of Reishi mushroom extract per serving (2 capsules). The formula uses a proprietary blend for some ingredients, so exact amounts for all 10 mushrooms are not publicly disclosed.

Are Cholibrium ingredients researched?

Yes, each of the 10 mushroom ingredients in Cholibrium has published research supporting its traditional use and potential health benefits. The formula was designed based on both traditional medicine practices and modern scientific studies on mushroom extracts.

Is Cholibrium vegetarian or vegan?

Yes, Cholibrium uses vegetarian capsules and contains no animal-derived ingredients. The formula is suitable for both vegetarians and vegans. It is also non-GMO, gluten-free, and free from common allergens.

What mushrooms are in Cholibrium?

Cholibrium contains 10 medicinal mushrooms: Reishi, Lion's Mane, Cordyceps, Shiitake, Maitake, Turkey Tail, Chaga, Royal Agaricus, White Button, and Black Fungus. Each was selected for its traditional use and research supporting cardiovascular health.

See the Full Ingredient List for Yourself

Every ingredient is backed by published research. The 6-bottle package gives you the best per-bottle price and covers the full 90-day recommended period.

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*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.